CHEM 657 - Total Synthesis of Natural Products

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The course will cover the total syntheses of selected natural products from animal, plant, marine, bacterial and fungal sources, including vitamins, alkaloids, hormones, terpenoids and antibiotics. Both historically significant total syntheses of landmarks, such as those of cholesterol, morphine, strychnine and vitamin B12, and the more modern total syntheses, such as those as taxol, bleomycin and enediyne antibiotics, will be elaborated. Students who opt to take the course for graduate credits (CHEM 657) will be required to write an additional term paper and/or make an oral presentation on the total synthesis of a selected natural product.