GPLS 709 - Advanced Biochemistry

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This advanced core course for the biochemistry program emphasizes protein structure and function, including the following topics: protein folding and stability; thermodynamics; allosteric interactions; protein structure/dynamics, the chemistry of enzyme mechanisms; steady-state and pre-steady state kinetics; and methods used for characterizing proteins and enzymes, including circular dichroism, nuclear magnetic resonance, X-ray diffraction, protein fluorescence and stopped-flow techniques. The course includes problem sets and two exams.