CHEM 472 - Enzyme Reaction Mechanisms (3)

The mechanism of enzyme action will be examined with emphasis on three-dimensional structure of enzymes, chemical catalysis, methods of determining enzyme mechanisms, stereochemistry of enzymatic reactions, detection of intermediates, affinity labels and suicide inhibitors, transition state analogs, energy relationships, evolutionarily “perfect” enzymes, genetic engineering and enzymes and use of binding energy in catalysis. Instruction will be in both lecture and seminar format, with emphasis on recent literature.

Grading: Graded/Satisfactory Unsatisfactory/Audit
Course ID: 52735
Consent: No Special Consent Required
Components: Lecture
Prerequisite: CHEM 352 and CHEM 437 with a grade of ‘C’ or better.